Rhinocerebral Mycosis: Combined Modality Protocol
نویسنده
چکیده
Rhinocerebral mycosis is an invasive fungal infection which occurs primarily in the paranasal sinuses and progresses to involve the brain and/or the orbit. It is commonly seen in immunocompromised individuals and can be most effectively treated if diagnosed early, when it is limited to the nasal cavity and the paranasal sinuses. Even though it is acceptable that surgical debridement in combination with antifungal therapy can lead to high rate of cure, the surgical approach for intracranial extension is still a subject of debate. Twenty-four cases of rhinocerebral mycosis managed at our institute are discussed, regarding presenting complaints and management.
منابع مشابه
Predictors of mortality in rhinocerebral mycosis.
INTRODUCTION Rhinocerebral mycosis is a rapidly progressive fatal opportunistic infection, predominantly affecting people in an immunocompromised state. Aggressive surgical therapy, with repeated debridement in combination with intravenous amphotericin B can lead to a high rate of cure. AIM To determine the predictors of mortality in rhinocerebral mycosis. MATERIALS AND METHODS The demograp...
متن کاملThe role of chemokines and chemokine receptors in mycosis fungoides
Background: Chemokines are a family of cytokines initially characterized by their capacity to induce chemotaxis, or directed leukocyte migrations. These receptors are activated by chemotactic cytokines called chemokines. Interactions between chemokines and chemokine receptors also are involved in tumorigenesis, migration and invasion of lymphoma cells.Methods: An English literature search...
متن کاملMultimodal Surgical and Medical Treatment for Extensive Rhinocerebral Mucormycosis in an Elderly Diabetic Patient: A Case Report and Literature Review
Diabetes is a well-known risk factor for invasive mucormycosis with rhinocerebral involvement. Acute necrosis of the maxilla is seldom seen and extensive facial bone involvement is rare in patients with rhino-orbital-cerebral mucormycosis. An aggressive surgical approach combined with antifungal therapy is usually necessary. In this report, we describe the successful, personalized medical and s...
متن کاملConcomitant Mucormycosis and Aspergillosis of Rhinocerebral Region in a Renal Transplant Patient – Air Cooler Being the Culprit
Invasive fungal infections are associated with morbidity and mortality in immunocompromised patients. Rhinocerebral region infections are mainly due to opportunistic fungal pathogens. Although Zygomycosis and Aspergillosis are two major causes of paranasal infections, reports of combined Mucormycosis and Aspergillosis infections of rhinocerebral region are limited. We report a case of fatal, co...
متن کاملResolution of rhinocerebral zygomycosis associated with adjuvant administration of granulocyte-macrophage colony-stimulating factor.
We successfully treated 3 consecutive patients who had nonneutropenic rhinocerebral zygomycosis, by use of subcutaneous granulocyte-macrophage colony-stimulating factor therapy combined with traditional surgical and medical treatment. All patients are currently free of disease. Granulocyte-macrophage colony-stimulating factor should be considered as adjuvant therapy for rhinocerebral zygomycosi...
متن کامل